Dual role of Cutibacterium acnes in acne vulgaris pathophysiology

The Role of Inflammation in Acne Vulgaris

22 PRACTICAL DERMATOLOGY AuGusT 2013 I nflammation has long been recognized as important in the pathogenesis of acne; however, until recently it was considered a secondary event. Studies over the past decade have demonstrated a central role for inflammation in the development of acne lesions and have opened new opportunities for therapeutic intervention.1,2,3 Understanding the role of inflammat...

Acne vulgaris--an update on pathophysiology and treatment.

Acne Vulgaris: a Review on Pathophysiology and Treatment

Acne vulgaris is a disease associated with sebaceous follicle. It starts appearing after the onset of puberty and can extend up to 40-50 years of age. As far as the pathogenesis of acne is concerned, it is not fully understood up till now. Treatment of acne is very frustrating and involves an understanding of etiopathological factors. This review focuses on various factors accountable, pathogen...

Acne sans P. acnes.

Acne vulgaris is a common disease that carries an enormous financial and psychosocial impact. Androgens, excessive sebum production, ductal hypercornification, changes in the microbial flora, as well as inflammation and immunological host reactions are considered the major contributors to acne pathogenesis. Despite extensive research on acne pathogenesis, the exact sequence of events and their ...

Identification of the Propionibacterium acnes using Polymerase Chain Reaction (PCR) in the Acne vulgaris lesions

Background: Acne vulgaris is an inflammatory chronic disease of pilosebaceous unit. One of the most important factors playing a role in occurrence of acne is presence of Propionibacterium acnes. With the aim of molecular identification of the P. acnes from the acne vulgaris lesions, current research was carried out. Methods: In this study, contents within the lesions was collected from 70 patie...